Marine Chimiodiversity knowledge and utilisation

Groupe leader: Professeur Gilles Barnathan

The third axis corresponds to chemistry devoted to the study of marine metabolites and their applications in numerous fields, such as health, nutrition or cosmetic.

Three thematics are included in this axis : the first two are mainly involved on the chemical aspect and the third one on the valorization.

ChimiMar (enzymatic engineering and chemistry of metabolites from invasive marine species) is studying high added value metabolites and the methods to obtain them. One of the main objectives is to upgrade invasive organisms of the Brittany shores. Studies are classified according to chemical classes (protein, pigment, lipid, fatty acid, sterol...) or to methodologies developed (enzymatic engineering, chromatography...).
Scientific coordination: Joël Fleurence et Gaëlle Penreac'h

FungiMar (Chimiodiversity, metabolomic and marine fungi) is totally devoted to fungal metabolites research. Indeed, fungi are powerful chemical factories and the marine ones have been more less described than the terrestrial ones. According to our experience, we have demonstrated that the salinity of culture medium induce the metabolite biosynthesis. Researches are devoted to marine fungal toxins and in peculiar on peptaïbols and dereplication and metabolomic procedures involved in the research of new marine molecules of interest.
Scientific coordination: Yves-François Pouchus et Olivier Grovel.

IngreMar IngreMar (marine molecule application in cosmetic, nutrition and health) is studying the use of marine molecules in fields such as cardiovascular protection or sunscreen. Needless to say that links exist between this thematic and the molecules isolated by ChimiMar and FungiMar.
Scientific coordination: Laurence Coiffard et Hassan Nazih.

In addition, a collection of marine fungal strains is managed by the CHIM team. Around 800 strains of fungi have been isolated in shellfishes, sediments, seawater coming from regional shellfish farming areas. Methods based on gene study are developped here to the strains' identification.
Scientific coordination: Thibaut Robiou du Pont.